RNs can coordinate clinical research trials, working with pharmaceutical companies, researchers, and healthcare institutions. This includes recruiting and screening trial participants, administering trial protocols, monitoring patient outcomes, and ensuring compliance with regulatory requirements.

Designing and running wellness retreats that focus on holistic health can be a unique business for RNs. The retreats can offer workshops on nutrition, mental health, stress reduction, exercise, and relaxation techniques, providing participants with a rejuvenating and educational experience.

RNs can start an agency that helps match travel nurses with healthcare facilities needing temporary staffing. This involves recruiting, credentialing, and placing travel nurses in various locations for short-term assignments. It's a growing field due to nurse shortages and provides flexibility and adventure for travel-loving nurses.

RNs with a knack for writing or creating videos can start a blog or vlog focusing on health topics. This can include writing informative articles or creating video content about medical conditions, health tips, patient care advice, and sharing personal experiences in nursing. Revenue can be generated through ads, sponsorships, and online courses.

Offering specialized care for elderly patients can be a lucrative business for RNs. Services can range from daily living assistance, medication management, chronic disease care, and companionship. This business caters to the growing aging population needing in-home care.

RNs can provide consultancy services to businesses aiming to improve workplace health and safety. This includes developing wellness programs, conducting health risk assessments, offering first aid training, and implementing policies to reduce workplace injuries and illnesses.

Registered Nurses with a passion for teaching can start a business offering education and training programs for aspiring nurses or continuing education for current healthcare professionals. This can include CPR certification, advanced clinical skills workshops, and preparation for nursing exams.

RNs can leverage their expertise to offer personalized health and wellness coaching. This includes creating nutrition plans, exercise regimens, stress management techniques, and lifestyle modifications for individuals looking to improve their overall health.

With advancements in technology, Registered Nurses can establish telehealth services to conduct virtual consultations and follow-ups. This covers routine check-ups, managing chronic conditions, providing health education, and triaging patients. It's a cost-effective way to reach patients in remote or underserved areas.

Registered Nurses can offer home healthcare services providing medical care to patients in their homes. Services can include wound care, medication administration, chronic disease monitoring, and patient education. This business allows for personalized care and flexibility for both the nurse and the patient.